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Research indicates that high doses of B12particularly from supplements or injectionsmay alter skin bacteria behaviour and inflammatory responses in some people

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This is consistent with our hypothesis that this group would include patients in whom excitotoxic damage during acute florid illness has led to subsequent reductions in mental and neural activity mediated by glutamatergic neurotransmission [3, 4]

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Moreover, a similar experiment with murine melanoma cells also marked the polymethoxy flavones to inhibit the melanogenesis process 116

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